Gong X, et al. – The specialists undertook this work to analyze the diagnostic value of 14-3-3η protein in early rheumatoid arthritis (RA) associated with secondary osteoporosis. Results showed that serum 14-3-3η protein levels were increased significantly in patients with RA (especially in early RA). Investigations also highlighted the relationships between serum 14-3-3η protein and clinical symptoms and osteoporosis in patients with RA.