Osuna-Prieto FJ, Martinez-Tellez B, Ortiz-Alvarez L, et al. - Researchers undertook this cross-sectional study to determine if and how plasma succinate levels are related to cardiovascular disease (CVD) risk among young adults. From the ACTIvating Brown Adipose Tissue through Exercise (ACTIBATE) study cohort, they included 100 (65% women) individuals aged 18–25 years. They found presence of higher levels of visceral adipose tissue (VAT) mass (+ 42.5%), triglycerides (+ 63.9%), C-reactive protein (+ 124.2%), diastolic blood pressure (+ 5.5%), and pro-inflammatory omega-6 oxylipins in participants with higher succinate levels vs those with lower succinate levels. Metabolically unhealthy people had higher succinate levels than healthy overweight/obese peers. Findings demonstrated an association of plasma succinate levels with a specific pro-inflammatory omega-6 signature pattern as well as with higher VAT levels, and plasma succinate levels appeared to indicate the cardiovascular status of young adults.