Di Bonito P, Pacifico L, Licenziati MR, et al. - In this cross-sectional multicenter study, researchers sought to compare cardiometabolic risk profile and preclinical signs of target organ damage in youth with normal and elevated blood pressure (BP), according to the American Academy of Pediatrics (AAP) guidelines. They involved 2,739 youth (5-17-year-old; 170 normal-weight, 610 overweight, and 1,959 with obesity) defined nonhypertensive by the AAP guidelines. Elevated BP has been defined as BP ≥ 90th to < 95th percentile for age, gender, and height in children or BP ≥ 120/80 to < 130/80 in adolescents. Data reported that the overall prevalence of elevated BP was 18.3% and increased significantly from normal-weight to obese youth. Elevated BP is associated with increased BMI, insulin resistance, and liver steatosis, with no significant target organ damage relative to normotensive youth.