Kim S, et al. - Researchers examined the effects on neonatal birth outcomes of prenatal use of electronic cigarettes (ECs) relative to those in conventional cigarette (CC) smokers and complete tobacco abstainers. They obtained data from 55,251 pregnant women who participated in the Phase 8 survey of the Pregnancy Risk Assessment Monitoring System between 2016 and 2018. Among participants, EC use was reported in 1.0% of women during the third trimester; of these, 60% reported exclusive EC use. Relative to neonates of tobacco abstainers, neonates of EC users were significantly more frequently SGA, or born preterm. However, there were significantly lower odds of EC users’ pregnancies resulting in SGA, LBW, or preterm birth relative to those of CC smokers. Per findings, EC use remains an independent risk factor for neonatal complications, even after accounting for shared risk factors between prenatal tobacco use and adverse birth outcomes, and is not a safer alternative to CC smoking during pregnancy.