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Elderly onset of early rheumatoid arthritis is a risk factor for bone erosions, refractory to treatment: KURAMA cohort

International Journal of Rheumatic Diseases Nov 16, 2018

Murata K, et al. - Authors gauged how old age at disease onset affects patient treatment and prognosis in early rheumatoid arthritis (RA). They divided the patients into the following two groups: The young-onset RA (YORA) including the patients <60 years old and elderly-onset RA (EORA) comprising patients ≥60 years old. More frequently, elderly-onset RA (EORA) was seen in bone erosions. Findings suggested that in order to protect bone erosions in the anti-citrullinated protein autoantibody (ACPA)-positive EORA patients, clinical remission at 1 or 2 years was not enough. They suggested the consideration of optimal treatment strategies preventing radiological damage for EORA. In EORA, the disease activity was higher than in YORA at baseline.
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