Kecici AS, et al. - In this prospective, open-label, single-arm trial, researchers sought to assess the effectiveness of maggot therapy (MT) for refractory cutaneous ulcers of Behçet disease (BD), as well as factors associated with therapy success rate and adverse events. Participants in the study were patients with BD with refractory leg ulcers suitable for MT. Maggot application was conducted until complete debridement was achieved, and all patients were followed up for 12 months afterwards to evaluate the total healing of ulcers. A total of 24 patients with 32 ulcers were registered. Time to debridement was positively associated with pretreatment ulcer size and ulcer duration but not with ulcer depth, comorbidities, smoking, age or gender. The authors discovered that 79.1% of all ulcers healed completely during follow‐up. Mean time needed for total healing was positively associated with ulcer duration, pretreatment and post‐treatment ulcer area, ulcer depth and mean time to total debridement. The findings of this pioneering and one-of-a-kind study may hold important clues to the factors influencing the success rate of MT in BD cutaneous ulcers.