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Efficacy of integrated exposure therapy vs integrated coping skills therapy for comorbid posttraumatic stress disorder and alcohol use disorder: A randomized clinical trial

JAMA Aug 14, 2019

Norman SB, Trim R, Haller M, et al. - For decreasing PTSD symptoms and alcohol use, researchers contrasted the effectiveness of integrated (ie, targeting both posttraumatic stress disorder [PTSD] and alcohol use) prolonged exposure (I-PE) therapy vs present-centered integrated coping skills (I-CS) therapy, a more ordinarily available treatment via a randomized clinical trial of 119 individuals. With both, linear mixture models discovered that PTSD symptoms were reduced, with a significantly greater reduction resulting from I-PE treatment vs I-CS treatment. The percentage of heavy drinking days got better with both, although it was not statistically distinct between I-PE and I-CS treatment. Hence, a greater decrease in PTSD symptoms in the I-PE arm vs the I-CS arm with similar drinking reductions was noted. Moreover, exposure therapy was more effective in treating PTSD vs the more ordinarily available integrated treatment, without exposure for comorbid PTSD and alcohol use disorder.

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