Watai K, et al. - Through a retrospective, cross-sectional study on 7,291 young patients with untreated intermittent adult-onset asthma, the contributors intended to determine the effects of short-term smoking (<10 pack-years) on lung function and airway hyper-responsiveness (AHR). A significant association between decreased postbronchodilator lung function and the daily smoking frequency, smoking duration, and cumulative smoking history was found. Even in patients with intermittent adult-onset asthma, short-term active smoking in early adulthood and decreased lung function and AHR might be linked. The benefits of never smoking, even for young patients with intermittent adult-onset asthma is suggestive.