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Effects of obesity on sperm retrieval, early embryo quality and clinical outcomes in men with nonobstructive azoospermia undergoing testicular sperm aspiration-intracytoplasmic sperm injection cycles

Andrologia Mar 15, 2019

Li F, et al. - Between January 2010 and June 2017, investigators analyzed 3005 infertile couples including 1585 normal-weight [body mass index (BMI) < 25 kg/m2], 847 overweight (BMI 25–29.99 kg/m2) and 573 obese (BMI ≥ 30 kg/m2,) candidates to assess the consequences of body mass index (BMI) on sperm retrieval, early embryo quality and clinical outcomes in individuals with nonobstructive azoospermia (NOA) undergoing testicular sperm aspiration-intracytoplasmic sperm injection (TESA-ICSI). They observed lower T levels and higher E2 levels among obese individuals when compared with normal-weight and overweight people. Although, they did not notice any significant difference in other male hormones like follicle stimulating hormone (FSH), luteinizing hormone (LH), or prolactin (PRL) among the groups. They did not find any impact of high BMI levels on sperm parameters, embryo quality, and clinical outcomes.
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