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Effects of nutritional supplementation and home visiting on growth and development in young children in Madagascar: A cluster-randomized controlled trial

The Lancet Global Health Aug 15, 2019

Galasso E, et al. - A total of 125 programme sites were randomized to five intervention by the researchers in order to examine the integration of lipid-based nutrient supplementation (LNS) and home visits within an existing, large-scale, community-based nutrition programme in Madagascar. The study recruited 3,738 mothers of which, 1,248 were pregnant women and 2,490 children aged 0–11 months at baseline who were evaluated at 1-year and 2-year intervals. No chief impacts of any of the intervention groups on any measure of anthropometry or any of the child development outcomes in the full sample was noted. However, compared with children in the standard-of-care programme with monthly growth monitoring and nutrition education (T0) intervention group, the youngest children in the T0 plus home visits for intensive nutrition counselling through an added community worker and LNS for children aged 6–18 months (T2) and T2 plus LNS for pregnant or lactating women intervention groups who were fully exposed to the child LNS dose had greater length-for-age Z scores and lower stunting prevalence. Supplementing mothers presented no further advantage. Hence, LNS for children for a term of 12 months only profited growth when it started at an early age, recommending the necessity to supplement infants at age 6 months in a very low-income context. The lack of influence of the early stimulation messages and home visits might be because of little take-up of behavior-change messages and delivery difficulties facing community health workers.
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