Zayed M, Nassar H, Hasanin A, et al. - Given that deliberate hypotension is used to afford a bloodless field during functional endoscopic sinus surgery; however, no extensive assessment of the influence of controlled hypotension during anesthesia on peripheral tissue perfusion has been carried out, and therefore, researchers undertook this randomized, double-blinded, controlled trial to compare the influence of nitroglycerin- vs labetalol-induced hypotension on peripheral perfusion. The final analysis included 40 adult patients undergoing endoscopic sinus surgery. Based on the drug administered for induction of deliberate hypotension, patients were either assigned to nitroglycerin (n = 20) or to labetalol (n = 20) group. In both groups, mean arterial pressure was maintained at 55–65 mmHg. Findings revealed that during sinus endoscopic surgery, nitroglycerin-induced deliberate hypotension vs labetalol-induced deliberate hypotension was accompanied by higher peripheral perfusion index as well as lower serum lactate levels.