Wilkinson DJ, et al. - In the under represented group of older women, the authors examined responses of muscle protein synthesis (MPS) to leucine-enriched essential amino acids (EAA) in comparison to a large bolus of whey protein (WP). Despite only providing 0.6 g of leucine, 1.5 g leucine-enriched EAA supplements (LEAA_1.5) robustly (perhaps maximally) stimulated MPS, with the negligible trophic advantage of greater doses of LEAA or even to 40 g WP. Underscoring that composition of EAA, in particular, the presence of leucine rather than the amount was most crucial for anabolism.