Correia MA, Oliveira PL, Farah BQ, et al. - Researchers performed this randomized controlled trial to assess how the cardiovascular function of patients with peripheral artery disease can be altered by isometric handgrip training (IHT). The participants were allocated to either the IHT or control group. The patients in the IHT group were asked to perform 3 sessions per week, for 8 weeks, of unilateral handgrip exercises, including 4 sets of isometric contractions for 2 minutes at 30% of maximum voluntary contraction and a 4-minute interval between sets. A compression ball was received by the controls for reducing the placebo effects, representing sham training. Brachial blood pressure (BP) was the primary outcome. Experts noted that a reduction in brachial diastolic BP and improvement in local vascular function was brought about by IHT in patients with peripheral artery disease.