Umphonsathien M, Rattanasian P, Lokattachariya S, et al. - High effectiveness of intermittent very-low calorie diet (VLCD) was observed in achieving optimal glycemic control in patients with type 2 diabetes and obesity. Relatively similar effects on diabetes remission were achieved with either 2 days/week or 4 days/week of intermittent VLCD in these patients.

• A total of 40 patients were randomized to the control group, to 2 days/week or 4 days/week of intermittent VLCD.

• At week 20, both intermittent VLCD groups showed improved glycemic control with significant reductions in glycated hemoglobin levels and insulin resistance index throughout the study periods.

• Significant reduction in serum triglyceride, bodyweight, body mass index and fat mass was evident in both VLCD groups.

• No serious adverse events occurred.