Juraschek SP, et al. - In a subpopulation of Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial participants (n = 23,964; mean age: 69.8 ± 6.8 years; 45% women; 31% non-Hispanic black) observed over a mean duration of 4.9 years, researchers assessed the impact of the selection of antihypertensive agent on the risk of falls, syncope, and orthostatic hypotension (OH) in older adults. They used Cox regression to evaluate the relative risk of falls, syncope, OH, or a composite based on Centers for Medicare and Medicaid Services and Veterans Affairs claims. Also, they used Cox models adjusted for age, sex, and race to investigate the adjusted link of self-reported atenolol use on outcomes. Findings revealed no influence of the choice of antihypertensive agent on the risk of fall, syncope, or OH long-term in older adults. However, a rise in the risk of falls was observed with 1 year of initiation of amlodipine. There was no link of atenolol use with any of the three individual or composite claims.