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Effectiveness of the 10-valent pneumococcal conjugate vaccine among girls, boys, preterm and low-birth-weight infants – Results from a randomized, double-blind vaccine trial

Vaccine May 26, 2019

Nieminen H, et al. - In order to assess PHiD-CV10 (10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine) efficacy in subgroups by sex, gestational age, and birth weight, researchers performed this post-hoc analysis of a phase III/IV cluster-randomized, double-blind trial (the FinIP trial) wherein PHiD-CV10 was reported to be effective on several endpoints. In both sexes, similar effectiveness of PHiD-CV10 was evident. Premature infants vs term infants had higher incidences of pneumonia outcomes. PHiD-CV10 appeared protective in preterm infants.
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