Effectiveness of spontaneous ovulation as monitored by urinary luteinizing hormone vs induced ovulation by administration of human chorionic gonadotropin in couples undergoing gonadotropin stimulated intrauterine insemination (IUI): A randomized controlled trial
BJOG: An International Journal of Obstetrics and Gynaecology Jun 14, 2019
Thomas S, et al. - Researchers conducted a randomized controlled trial comparing spontaneous ovulation monitored by urinary luteinizing hormone (LH) vs induced ovulation by the administration of human chorionic gonadotropin (hCG) regarding the efficacy in couples undergoing gonadotropin stimulated IUI. They randomized couples with unexplained infertility, mild endometriosis, mild male factor and polycystic ovarian syndrome, to LH group (Group A) where urinary LH was done daily to detect spontaneous ovulation or hCG group (Group B) where urinary hCG was administered as a trigger. Women undergoing gonadotropin-stimulated IUI had no significant difference in clinical pregnancy rates when urinary LH and hCG trigger as methods to time insemination were compared.
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