Wang J, Zhang Y, Chen Y, et al. - In this single-blind, randomized, prospective, non-inferiority trial, researchers sought to determine the efficacy of rehabilitation nursing program interventions in patients with acute ischemic stroke. This trial was carried out in three wards of neurology departments at a tertiary hospital in China. Eligible patients were stratified based on their weighted corticospinal tract lesion load and then randomly assigned to one of two groups: experimental (n = 121) or control (n = 103). The trial had 200 participants. With lower 95% confidence limits beyond the margins for primary outcomes, the rehabilitation nursing program was non-inferior to therapist-led treatment. Although both treatments had comparable effects, no definitive conclusion could be drawn. Adequately powered studies are needed.