Gómez-Soria I, Brandín-de la Cruz N, Zaldívar JNC, et al. - Researchers conducted the study for analyzing the long-term impacts of a personalized cognitive stimulation (PCS) program on global cognition, cognitive aspects, activities of daily living, anxiety, and depression in older adults with possible mild cognitive impairment (MCI). A 12-month follow-up analysis was performed in a single-blind, randomized clinical trial to investigate the long-term impacts of a 10-week PCS program assessing older adults' cognitive level, depression, and anxiety with possible MCI. Fifty older adults, 23 in the intervention group and 27 in the control group, were evaluated 12 months after the CS program. At 12 months, there were significant differences in global cognition, global orientation, and spatial orientation in favor of the intervention group, as measured by the Spanish version of the Mini-Mental Status Examination (MEC-35). A PCS program could help improve global cognition, as well as global and spatial orientation.