Farhan-Alanie MM, Lee Y, Underwood M, et al. - This research sought to correlate the risk of revision for primary cemented total knee replacement (TKR) performed with or without a tourniquet. Data were obtained from the National Joint Registry for all primary cemented TKRs performed in England and Wales between April 2003 and December 2003. Researchers used Kaplan-Meier plots and Cox regression to evaluate the influence of tourniquet use, age at time of surgery, sex and American Society of Anaesthesiologists classification on risk of revision for all-causes. In this study, 16,132 had surgery with a tourniquet and 842 had surgery without a tourniquet among 16,974 cases of primary cemented TKR. There was no evidence that using a tourniquet for primary cemented TKR offers a clinically important or statistically significant reduction in the risk of all-cause revision up to 13 years after surgery. According to the findings, surgeons should consider this evidence when deciding whether to use a tourniquet for cemented TKR.