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Effect of time between diagnosis and surgery in colorectal cancer patients on mortality

Journal of Clinical Oncology Feb 04, 2019

Fangman BD, et al. - Researchers investigated the impact of time from diagnosis to surgery on survival in patients diagnosed with AJCC stage II or stage III colorectal cancer between 4/2011 and 11/2015 and either underwent surgery or adjuvant chemotherapy within the University of Texas Southwestern system. By means of EMR, several pertinent data points were abstracted and abstracted data were retrospectively analyzed to determine if the number of days between diagnosis and surgery was correlated with increased survival. This study included 113 patients with complete data available, the average age at diagnosis was 62.6 and average follow-up time was 41.4 months. Median time to surgery was 21 days. From diagnosis to surgery, a mean of 42.7 days was reported for survivors and 61.7 days for nonsurvivors. Findings revealed a significant negative correlation between days between diagnosis and surgery and survival. This indicated that early surgical intervention may be an underappreciated indicator of quality colorectal cancer care.
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