Hayashi K, et al. - The study assesses the outcomes of manifest refraction spherical equivalent error on visual acuity at various distances in eyes that received a trifocal intraocular lens (IOL). The investigation included 30 patients (60 eyes), that went through bilateral implantation of a trifocal IOL (Alcon PanOptix TFNT00; Alcon Laboratories, Inc., Fort Worth, TX). The findings revealed significant improvement in near visual acuity but poor distance visual acuity in a manifest spherical equivalent error of slight myopia. However, in the case of slight hyperopia, there was worsening of both distance and near visual acuity in eyes with trifocal IOLs, suggesting while emmetropia is the optimum target, slight myopia is better to target refraction than slight hyperopia.