Thorén M, Dixit A, Escudero-Martínez I, et al. - In this investigation involving 22,184 patients (n = 18,318 received intravenous thrombolysis, n = 3,071 received intravenous thrombolysis+thrombectomy, n = 795 received thrombectomy), researchers studied the impact of recanalization, defined as the disappearance of radiological signs of occlusion at 22 to 36 hours, on development of early cerebral edema (CED) and parenchymal hemorrhage (PH) after recanalization therapy. Patients with signs of artery occlusion at baseline (either Hyperdense Artery Sign or CT/MRI angiographic occlusion) were selected from the SITS-International Stroke Treatment Registry. Data reported that recanalization occurred in 64.1%. Even after adjustment for a higher rate for PH in recanalized patients, recanalization was related to a lower risk for early CED in patients with acute ischemic stroke.