Larnkjær A, Michaelsen KF, Rytter MJH, et al. - Researchers conducted this randomized controlled trial to analyze the impact of probiotics on thymus size and C-reactive protein (CRP) in healthy Danish infants starting daycare. In addition, they explored connections between thymus size, CRP and recent infections. Participants in the study were 186 children who were randomized to a combination of Lactobacillus rhamnosus, LGG and Bifidobacterium animalis spp. lactis, BB-12 or placebo for 6 months. In Danish children at the age of starting daycare, the probiotic intervention had no impact on thymus size or CRP. Thymus size was inversely associated with CRP, diarrhea, and thymus index at the endpoint. In addition, it was linked to the absence from daycare due to respiratory or gastrointestinal infections.