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Effect of prior glaucoma surgery on intraocular pressure immediately after anti-vascular endothelial growth factor injection

Graefe's Archive for Clinical and Experimental Ophthalmology Aug 12, 2019

Lam J, Luttrell I, Ding L, et al. - Researchers conducted this single institution, experimental study to describe how prior incisional glaucoma surgery influences the intraocular pressure (IOP) elevation immediately following intravitreal anti-VEGF injections. Study participants with a history of incisional glaucoma surgery who were receiving anti-VEGF injections were enlisted as well as control eyes. For this investigation, they involved 10 eyes with a history of glaucoma surgery and 29 control eyes receiving anti-VEGF injections. In both surgical and control eyes, proliferative diabetic retinopathy was the most common indication for intravitreal anti-VEGF injection. According to findings, eyes with previous incisional glaucoma surgery showed a considerably reduced postinjection elevation of IOP and a quicker recovery of their IOP preinjection to within 10 mmHg. Incisional glaucoma surgery can be considered in patients where postinjection IOP elevation attenuation is necessary and other less invasive measures have failed.
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