Lange SM, Sharpe E, Hertzfeldt DN, et al. - In view of the difficulties often encountered in administering antibiotics to patients with specific medication allergies, researchers here examined if a penicillin or cephalosporin allergy raised the risk for not receiving correct timing of prophylactic antibiotics at cesarean delivery. Performing electronic medical record query, they identified all women undergoing cesarean delivery at Mayo Clinic Hospital and grouped them based on allergy status to penicillin/cephalosporins. They identified a total of 818 patients with a penicillin or cephalosporin allergy; 75 of these (9.2%) were not provided prophylactic antibiotic within 60 minutes prior to skin incision. On the other hand, 326 (6.9%) of the 4,744 patients without a penicillin or cephalosporin allergy were not provided their prophylactic antibiotic within 60 minutes prior to skin incision. Overall findings suggest that prophylactic antibiotics are less frequently administered within the recommended 60 minutes prior to surgical incision to patients with a penicillin or cephalosporin allergy. They emphasize the relevance of clear plans and communication for ensuring proper antibiotic administration at cesarean delivery to prevent surgical site infection.