Effect of moderately but persistently elevated lipid levels on risks of stroke and myocardial infarction in young Korean adults
Journal of the American Heart Association Jun 04, 2021
Park JB, Kim DH, Lee H, et al. - In this study, the relationship between persistently elevated low‐density lipoprotein‐cholesterol (LDL‐C) and/or triglyceride levels and the atherosclerotic cardiovascular disease risks in young adults were explored. Using the Korean National Health Insurance Service database, researchers performed a nationwide population‐based cohort study including a total of 1,887,853 statin‐naive adults aged 20 to 39 years, with LDL‐C < 190 mg/dL. It was shown that persistently elevated LDL‐C and triglyceride levels were associated with atherosclerotic cardiovascular disease risk in young Korean adults without severe hypercholesterolemia. Since their effects on lifetime atherosclerotic cardiovascular disease risk may become more pronounced over the life course, these lipid abnormalities should be considered risk factors in young adults.
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