Heisterberg MF, et al. - The impact of blocking the angiotensin II type I receptor (AT1R) upon the response to acute heavy resistance exercise in elderly human skeletal muscle is explored in this study. In general, there does not seem to be any impact of AT1R blocking upon satellite cell number or myogenic pathways in elderly men in the days after one bout of heavy resistance exercise. However, the greater suppression of myostatin may prove to be beneficial over a long term intervention designed to induce hypertrophy.