Effect of lorazepam with haloperidol vs haloperidol alone on agitated delirium in patients with advanced cancer receiving palliative care: Randomized clinical trial
JAMA Sep 24, 2017
Hui D, et al. - This randomized clinical study strived to compare the effect of lorazepam vs placebo as an adjuvant to haloperidol for persistent agitation in patients with delirium in the setting of advanced cancer. Compared with haloperidol alone, the addition of lorazepam to haloperidol resulted in a significantly greater reduction in agitation at 8 hours. To evaluate generalizability and adverse effects, further research was required.
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