Kjølhede P, et al. - In women following midline laparotomy for proven or assumed gynecological malignancies, researchers ascertained if regional analgesia with intrathecal morphine (ITM) in an enhanced recovery program (enhanced recovery after surgery) offers a shorter hospital stay with satisfactory pain relief and equivalent health-related quality of life (QoL) to epidural analgesia (EDA). In this open-label, randomized, single-center study involving 80 women (18-70 years of age), ITM is easier to administer and manage, was related to a shorter hospital stay, and postoperatively reduces opioid consumption with equally good QoL vs EDA. For the ITM group, length of hospital stay was statistically significantly shorter vs the EDA group. In gynecological cancer surgery, ITM is effective as postoperative analgesia. ITM or EDA have not been associated with any serious adverse events.