Price MO, et al. - A consecutive, single-center Descemet membrane endothelial keratoplasty (DMEK) case series was reviewed to assess whether a donor and/or recipient diabetes status influences the outcomes of Descemet membrane endothelial keratoplasty (DMEK). Although donor diabetes was related to a 5-fold increased risk of tissue preparation failure, it was not significantly associated with air reinjection, graft survival, or endothelial cell loss. This provides reassurance that tissue prepared successfully from donors with diabetes is safe to use for DMEK. Recipient diabetes was related to increased endothelial cell loss; the potential impact on longer-term graft survival merits further study.