Shrivastava AK, et al. - In this retrospective, observational study, researchers ascertained if different anterior chamber depth (ACD) affects the predictive accuracy of intraocular lens formulas in eyes with axial length (AL) less than 22 mm. This investigation was conducted at All India Institute of Medical Sciences, Raipur, India. The study sample consisted of 85 eyes of 85 patients with AL less than 22 mm. Study participants were divided into three groups: Group 1, ACD less than 2.4 mm; Group 2, ACD between 2.4 and 2.9 mm; and Group 3, ACD greater than 2.9 mm. In all cases, optical biometry with partial coherence interferometry was performed. The median absolute error was contrasted by Friedman’s test, utilizing the optimized lens constant, among seven formulas (Barrett Universal II, Haigis, Hill-RBF, Hoffer Q, Holladay 1, Holladay 2, and SRK/T) in each group. According to findings, considering the ACD in eyes with AL less than 22 mm, Haigis is the preferred formula whereas SRK/T was the worst formula in Groups 2 and 3.