Shanahan KH, et al. - In this retrospective cohort study, the researchers assessed early postnatal serum gut hormone concentrations in preterm infants as predictors of time to full enteral feedings as well as identified infant characteristics and nutritional factors that modulate serum gut hormone concentrations and time to full enteral feedings. Participants in the study were 64 preterm infants less than 30 weeks of gestation. They discovered that serum concentrations of glucose-dependent insulinotropic peptide (GIP) and peptide YY (PYY) on postnatal 7 were independently correlated with time to full enteral feedings. Data reported that the connection between serum gut hormone concentrations and time to full enteral feedings was not fully mediated by nutritional factors, implying an independent mechanism underlying the influence of gut hormones on feeding tolerance and time to full enteral feedings.