Coolen T, Lolli V, Sadeghi N, et al. - In a virtopsy framework the present study was undertaken to evaluate the occurrence of structural brain abnormalities in non-survivors of COVID-19. Researchers conducted a prospective, monocentric, case series study including consecutive patients who fulfilled the following inclusion criteria benefited from an early postmortem structural brain MRI: death < 24 hours, SARS-CoV-2 detection on nasopharyngeal swab specimen, chest CT scan suggestive of COVID-19, absence of known focal brain lesion, and MRI compatibility. In this study, 19 decedents fulfilled the inclusion criteria among the 62 patients who died of COVID-19 from March 31, 2020 to April 24, 2020 at the researchers' institution. In non-survivors of COVID-19, postmortem brain MRI illustrates hemorrhagic and PRES-related brain lesions. It was reported that SARS-CoV-2–related olfactory impairment appears to be limited to olfactory bulbs. It was shown that in COVID-19, brainstem MRI findings do not support a brain-related contribution to respiratory distress.