Naorungroj T, Neto AS, Zwakman-Hessels L, et al. - Researchers investigated if there exists a link between higher early net ultrafiltration (NUF) rates and increased mortality in continuous renal replacement therapy (CRRT) patients. They undertook this retrospective, observational study including all patients who received CRRT within 14 days of ICU admission. They described the early (first 48 h) NUF rate as the volume of fluid eliminated per hour adjusted for patient body weight and assessed as a categorical variable (> 1.75, 1.01–1.75 and < 1.01 mL/kg/h). In this study, 28-day mortality was the primary outcome. This analysis involved 347 patients {median age 64 years and Acute Physiology and Chronic Health Evaluation III score 73 [IQR 54–90]}. Findings revealed increased mortality in relation to NUF rates > 1.75 mL/kg/h vs early NUF rates < 1.01 mL/kg/h.