Michael J, et al. - In an equal-access, racially diverse prostate biopsy cohort, researchers assessed the link between lifetime alcohol intake and prostate cancer diagnosis. A survey was conducted including men undergoing prostate biopsy at the Durham Veterans Affairs Medical Center from 2007 to 2018. Average number of alcoholic beverages consumed per week (categorized as none, 1–6, ≥7) during each decade of life was approximated. Using multivariable logistic regression, the link between alcohol intake across decades and diagnosis of overall, low-grade (grade group [GG] 1–2) and high-grade prostate cancer (GG 3–5) was assessed. A positive association of heavier alcohol intake earlier in life and higher cumulative lifetime intake with high-grade prostate cancer diagnosis was seen, while no link was found between current intake and prostate cancer. Exploring earlier-life alcohol intake as a potential risk factor for high-grade prostate cancer was recommended.