Lopatkiewicz AM, Pera J, Slowik A, et al. - Since depression and apathy are often seen neuropsychiatric disturbances following stroke and may occur together, researchers sought to unravel the connection between early depressive and apathetic symptoms and outcome following stroke. There were 443 participants (median age: 69, 51% female) out of 698 patients enrolled with ischemic stroke that were evaluated for depressive and apathetic symptoms on day 8 of the stroke. Study participants were divided into 4 groups: without greater depressive and apathetic symptoms (Group 1), with only apathetic symptoms (Group 2), with only depressive symptoms (Group 3), and with both depressive and apathetic symptoms (Group 4). Group 2 and Group 4 had an increased risk of poor 3‐month outcome, after adjusting for age and stroke severity, as well as a higher risk of poor 12‐month outcome and mortality. Early apathetic symptoms are associated with worse outcomes after stroke, but not depressive symptoms were not. Apathetic symptoms should be recognized independently of depressive symptoms.