Severijns P, Moke L, Overbergh T, et al. - A prospective study was performed to evaluate the variations in sagittal alignment and compensation strategies in adult spinal deformity (ASD) between upright standing and walking, compared to control subjects and within different sagittal alignment groups. Researchers analyzed 10 patients pre-and six months postoperatively to evaluate the impact of surgical alignment correction on gait. The sample size included 58 ASD and 20 controls; Spinal kinematic analysis: 43 ASD and 18 controls; Post-operative analysis: 10 ASD. Researchers applied motion analysis to evaluate the standing and walking spinopelvic and lower limb kinematics, as well as the lower limb kinetics during walking. The data exhibited that patients with sagittal malalignment display altered lower limb gait patterns to compensate for elevated trunk tilt and pelvic anteversion during walking, which have previously been correlated with increased risk of falling and secondary lower limb pathology. Since the surgical correction of the deformity did not lead to gait improvements, a future study on the underlying mechanisms is needed to improve the understanding of how ASD impacts function.