Dopamine optimizes venous return during cardiopulmonary bypass and reduces the need for postoperative blood transfusion
ASAIO Journal Nov 14, 2019
Moscarelli M, Condello I, Fattouch K, et al. - In this single-center, double-blind case-control study, researchers investigated the role and utility of dopamine as a vasoconstrictor during cardiopulmonary bypass (CPB). Among 60 adults who were scheduled for isolated elective/urgent coronary artery bypass grafting, a dopamine bolus (2 mg) was provided 20 min after cross-clamping to patients in group A (n = 30), whereas no intervention at a specific time point was done in patients in group B (n = 30). Both groups received standard care as needed (fluid replacement or norepinephrine bolus). As per outcomes, the use of a dopamine bolus was correlated with an increase in venous return and reduction in the need for fluid replacement during and after CPB in patients undergoing coronary artery bypass grafting.
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