Akamatsu N, Hasegawa K, Egawa H, et al. - Researchers aimed at determining the possible risk factors, including relationship/HLA matching between donor and recipient, and immunosuppressive therapies for the recurrence of primary sclerosing cholangitis (PSC) after liver transplantation (LT). They assessed a total of 197 recipients of LT for PSC; of these, 180 recipients surviving more than 1 year after LT were included in further analysis for risk factors of recurrence. Observations revealed the 5‐ and 10‐year patient‐ and graft survival rates of 83% and 68%, and 71% and 62%, respectively. The overall PSC recurrence rate of 25% was recorded with a 5‐ and 10‐year graft survival rate of 34% and 18%, which was significantly lower relative to the survival rate of those without recurrence. In univariate analysis, donor age, cyclosporine use, mono or no immunosuppressive agent, postoperative biliary complication, and active intestinal bowel disease after LT were identified as risk factors for recurrence. The final multivariate Cox regression model revealed donor age ≥ 45 years and mono or no immunosuppressive agent 1‐year after LT as independent risk factors for recurrence.