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Does weight matter?: Outcomes in adult patients on venovenous extracorporeal membrane oxygenation when stratified by obesity class

Anesthesia & Analgesia Aug 21, 2020

Galvagno SM, Pelekhaty S, Cornachione CR, et al. - Researchers analyzed patients receiving venovenous (VV) extracorporeal membrane oxygenation (ECMO) for acute hypoxic or hypercarbic respiratory failure in this retrospective observational study, to examine the link between body mass index (BMI) and survival in this patient population. This study did not include patients < 18 years of age, listed for lung transplant, or underweight. Following stratification by BMI, ECMO outcomes including hospital length of stay and survival to discharge were assessed. As per the findings, obesity was not related to increased death in patients needing VV ECMO for acute hypoxic or hypercarbic respiratory failure. In view of these findings, candidacy for VV ECMO should not be excluded on account of obesity alone. These data may lend support to evidence for the “obesity paradox” in this group of VV ECMO patients.

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