Zak S, Yeroushalmi D, Long WJ, et al. - This study was attempted to explore the impact of tourniquet use on pain and opioid consumption following total knee arthroplasty (TKA). Researchers designed a multicenter randomized controlled trial among patients undergoing TKA. They randomized individuals preoperatively to undergo TKA with or without the use of an intraoperative tourniquet. They further used frequency distributions, means, and standard deviations to describe baseline patient demographics (age, gender, race, BMI, smoking status), length of stay, surgical factors, visual analogue scale pain scores, and opioid consumption in morphine milligram equivalents. The study enrolled a sum of 327 individuals in this study, with 166 patients undergoing TKA without tourniquet and 161 patients with the tourniquet. During TKA, the utilization of a tourniquet has minimal impact on postoperative pain scores and opioid consumption when compared to individuals who had undergone TKA without a tourniquet.