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Does induction of labor at term increase the risk of cesarean section in advanced maternal age? A systematic review and meta-analysis

European Journal of Obstetrics & Gynecology and Reproductive Biology Aug 28, 2020

Fonseca MJ, Santos F, Afreixo V, et al. - Researchers examined rates of cesarean delivery in correlation with induction of labor in advanced maternal age vs expectant management. From January 2000 to March 2020, they identified eight published studies, including 81151 pregnancies (26631 in the induction group and 54520 expectantly managed), for inclusion in the analysis. Analysis suggest that the results of retrospective studies comparing induction with spontaneous labor at the same gestational age mainly forms the basis of the belief that induction of labor is linked with an elevated risk of cesarean delivery. However, induction of labor and expectant management should be compared at any point in a pregnancy, with the latter contributing to a pregnancy of greater gestation age and not always resulting in spontaneous labor. When induction was compared with expectant management, this work indicated no significant raise in cesarean section, assisted vaginal delivery or postpartum hemorrhage.

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