Jahrami HA, Janahi A, Janahi M, et al. - Via this systematic review and meta-analysis, it was investigated how Ramadan diurnal intermittent fasting (RDIF; 29–30 days) could influence cardiometabolic risk factors (CMRF) in healthy adults. Also, through sub-group meta-regression, the impact of several cofactors on the outcomes was investigated. From ten scientific databases, 91 studies (4431 adults aged 18–85 years) were identified. Findings demonstrated a positive influence of RDIF on CMRF, which may offer short-term transient shielding against cardiovascular disease in healthy individuals. According to meta-regression, the significant moderator for alterations in both high-density lipoprotein cholesterol and very low-density lipoprotein cholesterol was the age of the fasting persons, while male gender was revealed as the only significant moderator for alterations in low-density lipoprotein cholesterol.