Abdelfattah R, et al. - A meta-analysis, including a dose-response analysis, was performed to evaluate the correlation between caffeine consumption and occurrence of atrial fibrillation (AF). They analyzed data from selected studies representing 176,675 subjects (AF in 9,987 [5.7%]). Findings revealed no increase in the AF occurrence by coffee consumption. Conversely, when caffeine consumption exceeded 436 mg/day, a lower incidence of AF was noted. Therefore, the available evidence suggests no association between caffeine intake and AF risk.