Braga A, et al. - Whether or not a human chorionic gonadotropin (hCG) level ≥ 20,000 IU/L four weeks after uterine evacuation for complete hydatidiform mole (CHM) is an appropriate indicator for initiating chemotherapy for the treatment of gestational trophoblastic neoplasia (GTN) was determined. A hCG level ≥ 20,000 IU/L four weeks after uterine evacuation for CHM was very predictive of post-molar GTN; however, a delay in treatment until the hCG level plateaued or increased did not affect outcomes, with no uterine perforations or treatment failures.