Alhamdow A, et al. - Researchers investigated if workplace polycyclic aromatic hydrocarbons (PAH) exposure increases the risk of cancer. They measured urinary PAH metabolites, the cancer-related markers telomere length (TL) and mitochondrial DNA copy number (mtDNAcn), and DNA methylation of lung cancer-related genes F2RL3 and AHRR in chimney sweeps, controls, and creosote-exposed male workers from Sweden. They found no links with PAH metabolites in urine (short-term exposure), however, PAH exposure was found to be associated with DNA hypomethylation of lung cancer-related loci; this was a dose-response link. These findings suggest that further protective measures should be taken to reduce PAH exposure.