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Disparities in survival for right-sided vs left-sided colon cancers in young patients: A study based on the Surveillance, Epidemiology, and End Results database (1990–2014)

Cancer Management and Research Jul 05, 2018

Wang Y, et al. - Researchers analyzed data from the Surveillance, Epidemiology, and End Results (SEER) database to see if young patients exhibit different features and survival according to tumor location and stage. They used Kaplan–Meier survival analysis and Cox proportional hazards regression for data analysis of young patients (20–49 years old) with stage I–III colon cancers. Subset analyses were also carried out among different age and stage subgroups. After adjusting for multiple clinicopathological features, they found that right-sided colon cancers (RCCs) vs left-sided colon cancers (LCCs) did not carry significantly different mortalities for all stages combined in patients younger than 50 years. However, lower mortality in stage II (especially in 20- to 39-year-old patients) and higher mortality in stage III (especially in 40- to 49-year-old patients) was reported for RCCs.

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