Kassebaum NJ, et al. - From 1990 to 2017, researchers estimated mortality and morbidity by age and sex in 195 countries and territories in children and adolescents. Data gathered from 1990 to 2017 in 195 nations and territories on children and adolescents from birth to 19 years of age were evaluated. According to results, child and adolescent fatalities reduced by 51.7% from 13.77 million in 1990 to 6.64 million in 2017, but overall disability increased by 4.7% in 2017 to 145 million years worldwide. Reductions in mortality over this span of 27 years imply that children are more likely to achieve their 20th birthdays than ever before. The concomitant development of non-fatal health loss and epidemiological transition in kids and adolescents, particularly in low-SDI and middle-SDI nations, has the capacity to boost already overburdened health systems, impact societies' human capital potential, and can impact the socio-economic development trajectory. Continued monitoring of child and adolescent health loss is critical to sustaining past 27 years' progress. Neonatal disorders, lower respiratory infections, diarrhea, malaria, and congenital birth defects were the major disaggregated causes of disability-adjusted life-years in 2017 in the low-SDI quintile, whereas neonatal disorders, congenital birth defects, headache, dermatitis, and anxiety were highest in the high-SDI quintile.