Ferri GM, et al. - In the present study, the researchers sought to assess the clinical presentation, diagnosis, and management of adult-onset laryngomalacia by literature review and report of a case. Databases for PubMed and Google Scholar were queried for articles published between 1960 and 2019 covering only patients aged 18 years and older. In total, 21 articles reported 41 cases of adult-onset laryngomalacia. Within these cases, five etiologies have been identified: neurologic, exercise-induced, post-operative, idiopathic, and age-related laryngomalacia. The most common laryngoscopic finding was anterior prolapse of arytenoids and aryepiglottic folds followed by posterior epiglottic prolapse. Adult laryngomalacia is a rare diagnosis involving a spectrum of disease. This diagnosis may be ignored, but attention should be given to the association with neurological injury or trauma. Patients often require surgical intervention as compared with pediatric laryngomalacia. Surgical decision is based on the direction of supraglottic collapse, where effective interventions are supraglottoplasty and partial epiglottidectomy.